Scar-reducing drug shows promise

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Scar
A scar is an area of tissue that replaces normal skin after an inury
BBC News

A drug designed to reduce scarring after surgery or injury has shown promising results in early human trials, UK researchers say.

Avotermin was tested in healthy volunteers with scars monitored over the period of a year.

The wounds injected with the treatment were less red, raised and visible than those treated with a dummy drug, The Lancet medical journal reported.

Further trials are now starting across Europe, the researchers said.

Early work on the drug was done at the University of Manchester before a spin-off biotechnology company - Renovo - was set up to develop it further.

People taking part in three trials were given identical 1cm full thickness skin incisions on both arms and were given an injection of avotermin in one and placebo in the other when the wounds were made and then 24 hours later.

Doctors assessing the subsequent appearance of the scars on a 100-point scale did not know which wound was treated with which drug.

The studies, which were done to test safety and find the best dose in more than 200 people, found the scars treated with avotermin looked more like normal skin than the scars treated with placebo. Read more...

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